Comparison of [18F]flortaucipir and [18F]MK6240 for the detection of tau pathology in Alzheimer's disease (HEAD): a multicentre, prospective, cross-sectional, within-participant study

May 30, 2026·
Guilherme Povala
,
Bruna Bellaver
,
Firoza Z. Lussier
,
Livia Amaral
Guilherme Bauer-Negrini
Guilherme Bauer-Negrini
,
Pamela C. L. Ferreira
,
Andreia Rocha
,
Emma Ruppert
,
Marina Scop Medeiros
,
Cécile Tissot
,
William J. Jagust
,
Joseph C. Masdeu
,
Juan Fortea
,
Dana L. Tudorascu
,
David N. Soleimani-Meigooni
,
Val J. Lowe
,
Hwamee Oh
,
Belen Pascual
,
Brian A. Gordon
,
Pedro Rosa-Neto
,
Suzanne L. Baker
,
Tharick A. Pascoal
· 0 min read
DOI
Type
Publication
The Lancet
Status
Peer-reviewed
publications
Guilherme Bauer-Negrini
Authors
Biomedical Data Scientist
Computational neuroscientist working at the intersection of machine learning, biomedical imaging, and human genetics in neurodegenerative disease. My work applies deep learning to high-dimensional medical images, harmonizes imaging measurements across sites and acquisition protocols, and integrates imaging with genomic, proteomic, and longitudinal clinical data to characterise Alzheimer’s disease and related dementias, with particular focus on fluid and imaging biomarkers of neurodegeneration.