Publications

Douglas Teixeira Leffa, Guilherme Bauer-Negrini, Livia Amaral, Bruna Bellaver, Pamela C. L. Ferreira, Guilherme Povala, Firoza Z. Lussier, João Pedro Ferrari-Souza, Ann D. Cohen, Dana L. Tudorascu, Samuele Cortese, Luis Augusto Rohde, Brooke S. G. Molina, Derek Archer, Tharick A. Pascoal (2026). Attention-deficit/hyperactivity disorder polygenic risk score and incidence of cognitive impairment in older adults: A prospective multicohort study. Alzheimer’s & Dementia.
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Guilherme Povala, Bruna Bellaver, Firoza Z. Lussier, Livia Amaral, Guilherme Bauer-Negrini, Pamela C. L. Ferreira, Andreia Rocha, Emma Ruppert, Marina Scop Medeiros, Cécile Tissot, William J. Jagust, Joseph C. Masdeu, Juan Fortea, Dana L. Tudorascu, David N. Soleimani-Meigooni, Val J. Lowe, Hwamee Oh, Belen Pascual, Brian A. Gordon, Pedro Rosa-Neto, Suzanne L. Baker, Tharick A. Pascoal (2026). Comparison of [18F]flortaucipir and [18F]MK6240 for the detection of tau pathology in Alzheimer's disease (HEAD): a multicentre, prospective, cross-sectional, within-participant study. The Lancet.
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Pamela C. L. Ferreira, Bruna Bellaver, Guilherme Povala, Guilherme Bauer-Negrini, Cristiano Schaffer Aguzzoli, João Pedro Ferrari-Souza, Douglas Teixeira Leffa, Carolina Soares, Firoza Z. Lussier, Marina Scop Medeiros, Cynthia Felix, Emma Ruppert, Francieli Rohden, Wyllians Vendramini Borelli, Helmet T. Karim, Rebecca Langhough, Bradley T. Christian, Rachael E. Wilson, Chang Hyung Hong, Hyun Woong Roh, Riddhi Patira, Dana L. Tudorascu, Eduardo R. Zimmer, Tobey J. Betthauser, Thomas K. Karikari, Beth E. Snitz, Sterling C. Johnson, Sang Joon Son, Tharick A. Pascoal (2026). Evaluating Plasma p-tau217 as an Endpoint for Alzheimer Disease Clinical Trials. Neurology.
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Guilherme Povala, Livia Amaral, Bruna Bellaver, Firoza Z. Lussier, Pamela C. L. Ferreira, Douglas Teixeira Leffa, Guilherme Bauer-Negrini, Raphael L. de Luca e Tuma, Álvaro de Oliveira Franco, Cécile Tissot, Quentin Finn, João Pedro Ferrari-Souza, Eduardo R. Zimmer, Dana L. Tudorascu, Joseph C. Masdeu, Juan Fortea, David N. Soleimani-Meigooni, Val J. Lowe, Hwamee Oh, Brian A. Gordon, Belen Pascual, Pedro Rosa-Neto, Suzanne L. Baker, Tharick A. Pascoal (2026). Low-dose CT for MRI-free quantification of tau PET in Alzheimer's disease: a multicentre, cross-sectional, comparison study. The Lancet Medical Imaging & Theranostics.
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Douglas Teixeira Leffa, Guilherme Povala, Pamela C. L. Ferreira, João Pedro Ferrari-Souza, Guilherme Bauer-Negrini, Matheus Scarpatto Rodrigues, Livia Amaral, Firoza Z. Lussier, Marina Scop Medeiros, Carolina Soares, Cristiano Schaffer Aguzzoli, Arthur C. Macedo, Joseph Therriault, Pedro Rosa-Neto, Dana L. Tudorascu, Eduardo R. Zimmer, Bruna Bellaver, Tharick A. Pascoal (2025). In vivo-measured Lewy body pathology is associated with neuropsychiatric symptoms across the Alzheimer’s disease continuum. Molecular Psychiatry.
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Carolina Soares, Bruna Bellaver, Pamela C. L. Ferreira, Guilherme Povala, Cristiano Schaffer Aguzzoli, João Pedro Ferrari-Souza, Hussein Zalzale, Firoza Z. Lussier, Francieli Rohden, Sarah Abbas, Guilherme Bauer-Negrini, Douglas Teixeira Leffa, Andréa L. Benedet, Rebecca Langhough, Tobey J. Betthauser, Bradley T. Christian, Rachael E. Wilson, Dana L. Tudorascu, Pedro Rosa-Neto, Thomas K. Karikari, Henrik Zetterberg, Kaj Blennow, Eduardo R. Zimmer, Sterling C. Johnson, Tharick A. Pascoal (2025). CSF total tau as a proxy of synaptic degeneration. Nature Communications.
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Sarah Abbas, Pamela C. L. Ferreira, Bruna Bellaver, Guilherme Povala, Francieli Rohden, Cristiano Schaffer Aguzzoli, Hussein Zalzale, João Pedro Ferrari-Souza, Douglas Teixeira Leffa, Firoza Z. Lussier, Carolina Soares, Guilherme Bauer-Negrini, Markley Silva Oliveira-Junior, Matheus Scarpatto Rodrigues, Pampa Saha, Emma Ruppert, Marina Scop Medeiros, Cécile Tissot, Joseph Therriault, Nesrine Rahmouni, Stijn Servaes, Andréa L. Benedet, Nicholas J. Ashton, Dana L. Tudorascu, Serge Gauthier, Helmet T. Karim, Chang Hyung Hong, Hyun Woong Roh, Eduardo R. Zimmer, Thomas K. Karikari, Henrik Zetterberg, Kaj Blennow, Anum Saeed, Sang Joon Son, Pedro Rosa-Neto, Tharick A. Pascoal, for Alzheimer’s Disease Neuroimaging Initiative (2025). Utility of plasma GFAP as a secondary endpoint for clinical trials in Alzheimer's disease. The Journal of Prevention of Alzheimer’s Disease.
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Francieli Rohden, Pamela C. L. Ferreira, Bruna Bellaver, João Pedro Ferrari-Souza, Cristiano Schaffer Aguzzoli, Carolina Soares, Sarah Abbas, Hussein Zalzale, Guilherme Povala, Firoza Z. Lussier, Douglas Teixeira Leffa, Guilherme Bauer-Negrini, Nesrine Rahmouni, Cécile Tissot, Joseph Therriault, Stijn Servaes, Jenna Stevenson, Andréa L. Benedet, Nicholas J. Ashton, Thomas K. Karikari, Dana L. Tudorascu, Henrik Zetterberg, Kaj Blennow, Eduardo R. Zimmer, Diogo Souza, Pedro Rosa-Neto, Tharick A. Pascoal (2025). Glial reactivity correlates with synaptic dysfunction across aging and Alzheimer's disease. Nature Communications.
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Bruna Bellaver, Guilherme Povala, Pamela C. L. Ferreira, Guilherme Bauer-Negrini, Firoza Z. Lussier, Douglas Teixeira Leffa, João Pedro Ferrari-Souza, Matheus Scarpatto Rodrigues, Livia Amaral, Markley S. Oliveira, Carolina Soares, Andreia Rocha, Pampa Saha, Nesrine Rahmouni, Arthur C. Macedo, Cécile Tissot, Joseph Therriault, Stijn Servaes, Jesse Klostranec, Maxime Montembeault, Andréa L. Benedet, Nicholas J. Ashton, Rebecca Langhough Koscik, Tobey J. Betthauser, Bradley T. Christian, Rachael E. Wilson, Gallen Triana-Baltzer, Paolo Vitali, Serge Gauthier, Henrik Zetterberg, Kaj Blennow, Thomas K. Karikari, Dana L. Tudorascu, Eduardo R. Zimmer, Sterling C. Johnson, Pedro Rosa-Neto, Tharick A. Pascoal (2025). Plasma GFAP for populational enrichment of clinical trials in preclinical Alzheimer's disease. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association.
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Douglas Teixeira Leffa, Guilherme Povala, Bruna Bellaver, João Pedro Ferrari-Souza, Pamela C. L. Ferreira, Firoza Z. Lussier, Cristiano Schaffer Aguzzoli, Carolina Soares, Hussein Zalzale, Francieli Rohden, Guilherme Bauer-Negrini, Sarah Abbas, Maitê Schneider, Joseph Therriault, Oscar L. Lopez, Victor L. Villemagne, William E. Klunk, Dana L. Tudorascu, Ann D. Cohen, Pedro Rosa-Neto, Eduardo R. Zimmer, Thomas K. Karikari, Luis Augusto Rohde, Brooke S. G. Molina, Tharick A. Pascoal, Alzheimer's Disease Neuroimaging Initiative (2025). Impact of the polygenic risk scores for attention-deficit/hyperactivity disorder in Alzheimer's disease. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association.
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