Subjective cognitive decline (SCD) is defined as a memory complaint in individuals without an objective measure of cognitive impairment. In this study, we investigated the morphometric and metabolic brain changes in individuals presenting with SCD. Compared to CU individuals, SCD subjects showed increased cortical thickness in the right hemisphere rostral middle frontal gyrus, while glucose metabolism was increased in the right medial temporal lobe, including the hippocampus, and right occipital cortex.
Andrei Bieger, Laura Willers Souza, Wyllians Vendramini Borelli, Guilherme Bauer Negrini, Guilherme Povala, Marco Antônio De Bastiani, Cécile Tissot, João Pedro Ferrari‐Souza, Raphael Machado Castilhos, Diogo O Souza, Pedro Rosa‐Neto, Tharick A Pascoal, Artur Francisco Schumacher‐Schuh, Jonathan M DuBois, Eduardo R Zimmer